The Integrated Stress Response in Lung Disease
نویسندگان
چکیده
منابع مشابه
Hyperoxia-induced activation of the integrated stress response in the newborn rat lung.
Diverse environmental stresses stimulate eukaryotic translation initiation factor 2α (eIF2α) phosphorylation, leading to a stress-resistant state characterized by global attenuation of protein synthesis and induction of cytoprotective genes. The signal transduction network culminating in these effects is referred to as the integrated stress response (ISR) or, when initiated by misfolded protein...
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ژورنال
عنوان ژورنال: American Journal of Respiratory Cell and Molecular Biology
سال: 2014
ISSN: 1044-1549,1535-4989
DOI: 10.1165/rcmb.2014-0019tr